TY - JOUR
T1 - Metrology and nano-mechanical tests for nano-manufacturing and nano-bio interface
T2 - Challenges & future perspectives
AU - Koumoulos, E. P.
AU - Tofail, S. A.M.
AU - Silien, C.
AU - De Felicis, D.
AU - Moscatelli, R.
AU - Dragatogiannis, D. A.
AU - Bemporad, E.
AU - Sebastiani, M.
AU - Charitidis, C. A.
N1 - Publisher Copyright:
© 2017 Elsevier Ltd
PY - 2018/1/5
Y1 - 2018/1/5
N2 - Nanometrology refers to measurement techniques that assess materials properties at the nanoscale. Laboratory-based characterisation of nanomaterials has been the key enabler in the growth of nanotechnology and nano-enabled products. Due to the small size involved, dimensional measurements has dominated such characterisation underpinned by a tremendous development in stand-alone electron/ion microscopes and scanning probe microscopes. However, the scope of nanometrology extends far beyond off-site, laboratory-based measurements of dimensions only, and is expected to have a tremendous impact on design of nano-enabled materials and devices. In this article, we discuss some of the available techniques for laboratory-based characterisation of mechanical and interfacial properties for nanometrology. We also provide a deep insight into the emerging techniques in measuring these properties, keeping in view the need in advanced manufacturing and nanobio-interactions to develop multifunctional instrumentation, traceable and standardized methods, and modelling tools for unambiguous data interpretation. We also discuss the evaluation of nanomechanical properties and surface/interface response of materials, within the purview of manufacturing processes and standardization. Finally, we discuss scientific and technological challenges that are required to move towards real-time nano-characterisation for rapid, reliable, repeatable and predictive metrology to underpin upscaling nanomaterials and nano-enabled products from the research field to industry and market.
AB - Nanometrology refers to measurement techniques that assess materials properties at the nanoscale. Laboratory-based characterisation of nanomaterials has been the key enabler in the growth of nanotechnology and nano-enabled products. Due to the small size involved, dimensional measurements has dominated such characterisation underpinned by a tremendous development in stand-alone electron/ion microscopes and scanning probe microscopes. However, the scope of nanometrology extends far beyond off-site, laboratory-based measurements of dimensions only, and is expected to have a tremendous impact on design of nano-enabled materials and devices. In this article, we discuss some of the available techniques for laboratory-based characterisation of mechanical and interfacial properties for nanometrology. We also provide a deep insight into the emerging techniques in measuring these properties, keeping in view the need in advanced manufacturing and nanobio-interactions to develop multifunctional instrumentation, traceable and standardized methods, and modelling tools for unambiguous data interpretation. We also discuss the evaluation of nanomechanical properties and surface/interface response of materials, within the purview of manufacturing processes and standardization. Finally, we discuss scientific and technological challenges that are required to move towards real-time nano-characterisation for rapid, reliable, repeatable and predictive metrology to underpin upscaling nanomaterials and nano-enabled products from the research field to industry and market.
KW - Bio
KW - Microscopy
KW - Nanoindentation, AFM
KW - Nanometrology
KW - Nanoscopy
UR - http://www.scopus.com/inward/record.url?scp=85032032412&partnerID=8YFLogxK
U2 - 10.1016/j.matdes.2017.10.035
DO - 10.1016/j.matdes.2017.10.035
M3 - Review article
AN - SCOPUS:85032032412
SN - 0264-1275
VL - 137
SP - 446
EP - 462
JO - Materials and Design
JF - Materials and Design
ER -
