TY - JOUR
T1 - Microbial advanced biofuels production
T2 - Overcoming emulsification challenges for large-scale operation
AU - Heeres, Arjan S.
AU - Picone, Carolina S.F.
AU - van der Wielen, Luuk A.M.
AU - Cunha, Rosiane L.
AU - Cuellar, Maria C.
N1 - Copyright © 2014 Elsevier Ltd. All rights reserved.
PY - 2014/4
Y1 - 2014/4
N2 - Isoprenoids and alkanes produced and secreted by microorganisms are emerging as an alternative biofuel for diesel and jet fuel replacements. In a similar way as for other bioprocesses comprising an organic liquid phase, the presence of microorganisms, medium composition, and process conditions may result in emulsion formation during fermentation, hindering product recovery. At the same time, a low-cost production process overcoming this challenge is required to make these advanced biofuels a feasible alternative. We review the main mechanisms and causes of emulsion formation during fermentation, because a better understanding on the microscale can give insights into how to improve large-scale processes and the process technology options that can address these challenges.
AB - Isoprenoids and alkanes produced and secreted by microorganisms are emerging as an alternative biofuel for diesel and jet fuel replacements. In a similar way as for other bioprocesses comprising an organic liquid phase, the presence of microorganisms, medium composition, and process conditions may result in emulsion formation during fermentation, hindering product recovery. At the same time, a low-cost production process overcoming this challenge is required to make these advanced biofuels a feasible alternative. We review the main mechanisms and causes of emulsion formation during fermentation, because a better understanding on the microscale can give insights into how to improve large-scale processes and the process technology options that can address these challenges.
KW - Advanced biofuels
KW - Bioemulsifiers
KW - Biosurfactants
KW - Multiphase fermentation
KW - Oil recovery
KW - Pickering stabilization
UR - http://www.scopus.com/inward/record.url?scp=84896543544&partnerID=8YFLogxK
U2 - 10.1016/j.tibtech.2014.02.002
DO - 10.1016/j.tibtech.2014.02.002
M3 - Review article
C2 - 24630476
AN - SCOPUS:84896543544
SN - 0167-7799
VL - 32
SP - 221
EP - 229
JO - Trends in Biotechnology
JF - Trends in Biotechnology
IS - 4
ER -