Abstract
Perinatal asphyxia is an obstetric complication that can induce serious complications in the central nervous system. Between 15% and 20% of newborns die immediately after birth and 25% survive with varied neurological deficits such as cerebral palsy, mental retardation and developmental delay. Although different treatments have been used, thus far only hypothermia is recommended as a routine treatment in clinical practice. In this chapter we will discuss the use of estradiol and its impact on the long-term deficits induced by perinatal asphyxia.
| Original language | English |
|---|---|
| Title of host publication | Estrogen Effects on Traumatic Brain Injury |
| Subtitle of host publication | Mechanisms of Neuroprotection and Repair |
| Publisher | Elsevier Inc. |
| Pages | 113-124 |
| Number of pages | 12 |
| ISBN (Electronic) | 9780128017074 |
| ISBN (Print) | 9780128014790 |
| DOIs | |
| Publication status | Published - 8 Jan 2015 |
| Externally published | Yes |
Keywords
- Estradiol
- Hippocampus
- Neuroprotection
- Perinatal asphyxia
- Striatum