NOT VISCOUS DRAG BUT MATRIC FORCES ARE RESPONSIBLE FOR SKIN BARRIER FUNCTION

Patricia M. van Kemenade, Jacques M. Huyghe, Lucien F.A. Douven

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The outermost layer of the skin, the stratum corneum is only about 20 microns thick, yet plays an important role in preventing an excessive loss of body fluids to the dry environment. By damaging the stratum corneum (mechanically or chemically) the transepidermal water loss (TEWL) increases. For instance removing the whole stratum corneum by stripping the skin with adhesive tape increases the water loss by 10 times (Lo et al., 1990), and after two successive exposures of skin to a detergent solution water loss is almost twice the basal value (Barel et al., 1995).

Original languageEnglish
Title of host publicationAdvances in Bioengineering
PublisherAmerican Society of Mechanical Engineers (ASME)
Pages35-36
Number of pages2
ISBN (Electronic)9780791818237
DOIs
Publication statusPublished - 1997
Externally publishedYes
EventASME 1997 International Mechanical Engineering Congress and Exposition, IMECE 1997 - Advances in Bioengineering - Dallas, United States
Duration: 16 Nov 199721 Nov 1997

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume1997-H

Conference

ConferenceASME 1997 International Mechanical Engineering Congress and Exposition, IMECE 1997 - Advances in Bioengineering
Country/TerritoryUnited States
CityDallas
Period16/11/9721/11/97

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