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Organic synthesis by Twin Screw Extrusion (TSE): Continuous, scalable and solvent-free
Deborah E. Crawford
, Clodagh K.G. Miskimmin
, Ahmad B. Albadarin
,
Gavin Walker
, Stuart L. James
Centre for Research Training in Foundations of Data Science
Department of Chemical Sciences
Pharmaceutical Manufacturing Technology Centre (PMTC)
SSPC - the Research Ireland Centre for Pharmaceuticals
Queen's University Belfast
University of Limerick
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Chemistry
Knoevenagel Condensation
100%
Metal Organic Framework
50%
Water Vapor
50%
Mechanochemistry
50%
Condensation Reaction
50%
Michael Addition
50%
Aldol Reaction
50%
Deep Eutectic Solvent
50%
formation
50%
Grinding (Machining)
50%
Imine
50%
Engineering
Knoevenagel Condensation
100%
Manufacturing Process
50%
Reactant
50%
Eutectics
50%
Elevated Temperature
50%
Extrusion Process
50%
Grinding (Machining)
50%
Condensation Reaction
50%
Material Science
Metal-Organic Framework
100%
Water Vapor
100%
Mechanochemical Synthesis
100%
Deep Eutectic Solvent
100%
Chemical Engineering
Metal-Organic Frameworks
100%
Condensation Reaction
100%