TY - JOUR
T1 - Palladium(II) complexes with N-alkyliminodiacetic acid derivatives
T2 - Preparation, structural and spectroscopic studies
AU - Smrečki, Neven
AU - Kukovec, Boris Marko
AU - Rotim, Katarina
AU - Oršolić, Daniela
AU - Jović, Ozren
AU - Rončević, Tomislav
AU - Mužinić, Nikolina Režić
AU - Vinković, Marijana
AU - Popović, Zora
N1 - Publisher Copyright:
© 2017 Elsevier B.V.
PY - 2017
Y1 - 2017
N2 - The reactions of N-alkyl derivatives of iminodiacetic acid, RN(CH2COOH)2 (i-PridaH2 and t-BuidaH2; i-Pr = isopropyl, t-Bu = tert-butyl) with sodium tetrachloropalladate(II) in aqueous solutions were investigated. Four new palladium(II) complexes {[Na[PdCl(i-Prida)](H2O)2]·1/2H2O}n (1), [Na[PdCl(t-Buida)](H2O)2]n (2), [Pd(i-PridaH)2]·2H2O (3) and [Pd(t-BuidaH)2] (4) were obtained and characterized by X-ray crystallography, infrared spectroscopy, 1H and 13C NMR spectroscopy, UV–Vis spectroscopy and thermal analysis (TG/DTA). In the solid state, the palladium(II) ion has square-planar coordination in all four complexes, composed of an O,N,O'-tridentate iminodiacetate ligand and a chloride ion in 1 and 2 and of two N,O-bidentate hidrogeniminodiacetate ligands in 3 and 4. Moreover, 1 is 2D coordination polymer composed of sodium ion clusters bridged by [PdCl(i-Prida)]− moieties, 2 is 1D coordination polymer composed of a zig-zag chain of sodium ions bridged by [PdCl(t-Buida)]− moieties and water molecules, while complexes 3 and 4 are monomeric species. Substitution of the chloride ligands in [PdCl(i-Prida)]− and [PdCl(t-Buida)]− by water molecules takes place after dissolution of the complexes 1 and 2, leading to formation of [Pd(i-Prida)(H2O)] (1') and [Pd(t-Buida)(H2O)] (2') species. Spectrophotometric potentiometric titration revealed that [PdCl(i-Prida)]− and [PdCl(t-Buida)]− are stable in acidic aqueous solution in the pH range 3–6 in the presence of chloride ions at [Cl−] > 0.1 M. Complexes 3 and 4 partially decompose upon dissolution in dimethyl sulfoxide, giving mixtures of the original complexes and by-products whose NMR spectra resemble those of 1' and 2'. Antibacterial and antitumor properties of the water-soluble complexes 1' and 2' were also investigated.
AB - The reactions of N-alkyl derivatives of iminodiacetic acid, RN(CH2COOH)2 (i-PridaH2 and t-BuidaH2; i-Pr = isopropyl, t-Bu = tert-butyl) with sodium tetrachloropalladate(II) in aqueous solutions were investigated. Four new palladium(II) complexes {[Na[PdCl(i-Prida)](H2O)2]·1/2H2O}n (1), [Na[PdCl(t-Buida)](H2O)2]n (2), [Pd(i-PridaH)2]·2H2O (3) and [Pd(t-BuidaH)2] (4) were obtained and characterized by X-ray crystallography, infrared spectroscopy, 1H and 13C NMR spectroscopy, UV–Vis spectroscopy and thermal analysis (TG/DTA). In the solid state, the palladium(II) ion has square-planar coordination in all four complexes, composed of an O,N,O'-tridentate iminodiacetate ligand and a chloride ion in 1 and 2 and of two N,O-bidentate hidrogeniminodiacetate ligands in 3 and 4. Moreover, 1 is 2D coordination polymer composed of sodium ion clusters bridged by [PdCl(i-Prida)]− moieties, 2 is 1D coordination polymer composed of a zig-zag chain of sodium ions bridged by [PdCl(t-Buida)]− moieties and water molecules, while complexes 3 and 4 are monomeric species. Substitution of the chloride ligands in [PdCl(i-Prida)]− and [PdCl(t-Buida)]− by water molecules takes place after dissolution of the complexes 1 and 2, leading to formation of [Pd(i-Prida)(H2O)] (1') and [Pd(t-Buida)(H2O)] (2') species. Spectrophotometric potentiometric titration revealed that [PdCl(i-Prida)]− and [PdCl(t-Buida)]− are stable in acidic aqueous solution in the pH range 3–6 in the presence of chloride ions at [Cl−] > 0.1 M. Complexes 3 and 4 partially decompose upon dissolution in dimethyl sulfoxide, giving mixtures of the original complexes and by-products whose NMR spectra resemble those of 1' and 2'. Antibacterial and antitumor properties of the water-soluble complexes 1' and 2' were also investigated.
KW - Coordination polymer
KW - Iminodiacetate
KW - Palladium(II)
KW - Spectrophotometric potentiometric titration
UR - http://www.scopus.com/inward/record.url?scp=85015388273&partnerID=8YFLogxK
U2 - 10.1016/j.ica.2017.03.010
DO - 10.1016/j.ica.2017.03.010
M3 - Article
AN - SCOPUS:85015388273
SN - 0020-1693
VL - 462
SP - 64
EP - 74
JO - Inorganica Chimica Acta
JF - Inorganica Chimica Acta
ER -