TY - JOUR
T1 - Particulate Matter and Hospital Admissions for Stroke in Beijing, China
T2 - Modification Effects by Ambient Temperature
AU - Huang, Fangfang
AU - Luo, Yanxia
AU - Guo, Yuming
AU - Tao, Lixin
AU - Xu, Qin
AU - Wang, Chao
AU - Wang, Anxin
AU - Li, Xia
AU - Guo, Jin
AU - Yan, Aoshuang
AU - Guo, Xiuhua
N1 - Publisher Copyright:
© 2016 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley Blackwell.
PY - 2016/7/6
Y1 - 2016/7/6
N2 - Background-—The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature. We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013–2014. Methods and Results-—A time-stratified case-crossover design was used to assess the relation between PM of different particle sizes and hospital admissions for ischemic and hemorrhagic stroke. Stratified analyses were performed by age, sex, and temperature. In total, there were 147 624 stroke admissions during the study period. In the whole-period analysis, both PM2.5 and PM10 were positively associated with ischemic stroke admissions on the day of hospital admission and negatively associated with ischemic stroke at lag2 and lag3 day. In warm days (>13.5°C), the odds ratios of ischemic stroke admissions were 2.071 (95% CI 1.959–2.190), 1.470 (95% CI 1.391–1.554), and 1.590 (95% CI 1.493–1.694) per IQR increase in the same-day PM2.5 (82.0 lg/ m3), PM2.5–10 (36.6 lg/m3), and PM10 (93.5 lg/m3), respectively. For hemorrhagic stroke, the corresponding values were 1.941 (95% CI 1.658–2.273), 1.590 (95% CI 1.366–1.851), and 1.527 (95% CI 1.278–1.826). The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C). Conclusions-—This study suggests that the associations of PM2.5, PM2.5–10, and PM10 with stroke admissions differed across levels of temperature. Short-term exposure to PM2.5, PM2.5–10, and PM10 was positively associated with hospital admissions for ischemic and hemorrhagic stroke on warm days (>13.5°C).
AB - Background-—The impact of particulate matter (PM) on stroke may vary by particle size, stroke subtype, and patient characteristics and temperature. We examined the association of stroke admissions with PM in different subgroups in Beijing, China, during 2013–2014. Methods and Results-—A time-stratified case-crossover design was used to assess the relation between PM of different particle sizes and hospital admissions for ischemic and hemorrhagic stroke. Stratified analyses were performed by age, sex, and temperature. In total, there were 147 624 stroke admissions during the study period. In the whole-period analysis, both PM2.5 and PM10 were positively associated with ischemic stroke admissions on the day of hospital admission and negatively associated with ischemic stroke at lag2 and lag3 day. In warm days (>13.5°C), the odds ratios of ischemic stroke admissions were 2.071 (95% CI 1.959–2.190), 1.470 (95% CI 1.391–1.554), and 1.590 (95% CI 1.493–1.694) per IQR increase in the same-day PM2.5 (82.0 lg/ m3), PM2.5–10 (36.6 lg/m3), and PM10 (93.5 lg/m3), respectively. For hemorrhagic stroke, the corresponding values were 1.941 (95% CI 1.658–2.273), 1.590 (95% CI 1.366–1.851), and 1.527 (95% CI 1.278–1.826). The positive associations were also observed in the other lag structures and were higher than in cold days (≤13.5°C). Conclusions-—This study suggests that the associations of PM2.5, PM2.5–10, and PM10 with stroke admissions differed across levels of temperature. Short-term exposure to PM2.5, PM2.5–10, and PM10 was positively associated with hospital admissions for ischemic and hemorrhagic stroke on warm days (>13.5°C).
KW - air pollution
KW - hospital admission
KW - particulate matter
KW - stroke
UR - http://www.scopus.com/inward/record.url?scp=85013801967&partnerID=8YFLogxK
U2 - 10.1161/JAHA.116.003437
DO - 10.1161/JAHA.116.003437
M3 - Article
C2 - 27413045
AN - SCOPUS:85013801967
SN - 2047-9980
VL - 5
JO - Journal of the American Heart Association
JF - Journal of the American Heart Association
IS - 7
M1 - e003437
ER -