Abstract
A novel approach is described for generating reactive oxidizing centers in heme proteins, with zinc hemoglobin (Zn Hb) and zinc cytochrome c (Zn cyt c) used as examples. The reaction of 3Zn* Hb with [CoIII(NH3)5 Cl]2+, and of 3Zn* cyt c with methyl viologen are described. In the case of Zn Hb the cation radical produced decays with a rate constant of k3 = 2400s-1. Using this value the rate of the reaction αZn+.βFe(III), k2→αZnβ Fe(III) can be calculated to be 4500s-1.
Original language | English |
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Pages (from-to) | 472-476 |
Number of pages | 5 |
Journal | Biochemical and Biophysical Research Communications |
Volume | 159 |
Issue number | 2 |
DOIs | |
Publication status | Published - 15 Mar 1989 |
Externally published | Yes |