Physicochemical n-Grams Tool: A tool for protein physicochemical descriptor generation via Chou’s 5-step rule

Shubham Vishnoi; Prabha Garg; Pooja Arora

doi:10.1111/cbdd.13617

Physicochemical n-Grams Tool: A tool for protein physicochemical descriptor generation via Chou’s 5-step rule

Shubham Vishnoi, Prabha Garg, Pooja Arora

National Institute of Pharmaceutical Education and Research, Mohali

Research output: Contribution to journal › Article › peer-review

Abstract

Physicochemical n-Grams Tool (PnGT) is an open-source standalone software for calculating physicochemical descriptors of protein. PnGT was developed using the Python scripting language and developed the user interface using Tkinter. The software currently calculates 33 physicochemical descriptors along with the sequence length for the given protein primary sequence. The descriptor generated by this tool can be directly utilized as the feature vector for the development of proteomics statistical or machine learning predictive model.

Original language	English
Pages (from-to)	79-86
Number of pages	8
Journal	Chemical Biology and Drug Design
Volume	95
Issue number	1
DOIs	https://doi.org/10.1111/cbdd.13617
Publication status	Published - 1 Jan 2020
Externally published	Yes

Keywords

descriptor generation
machine learning
n-Grams
physicochemical parameter
proteomics science

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10.1111/cbdd.13617

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abstract = "Physicochemical n-Grams Tool (PnGT) is an open-source standalone software for calculating physicochemical descriptors of protein. PnGT was developed using the Python scripting language and developed the user interface using Tkinter. The software currently calculates 33 physicochemical descriptors along with the sequence length for the given protein primary sequence. The descriptor generated by this tool can be directly utilized as the feature vector for the development of proteomics statistical or machine learning predictive model.",

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Physicochemical n-Grams Tool: A tool for protein physicochemical descriptor generation via Chou’s 5-step rule

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Keywords

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