TY - JOUR
T1 - Pilot randomized trial of progressive resistance exercise augmented by neuromuscular electrical stimulation for people with multiple sclerosis who use walking aids
AU - Coote, Susan
AU - Hughes, Lonan
AU - Rainsford, Gary
AU - Minogue, Conor
AU - Donnelly, Alan
N1 - Publisher Copyright:
© 2015 American Congress of Rehabilitation Medicine.
PY - 2015/2/1
Y1 - 2015/2/1
N2 - Objective To investigate the feasibility and preliminary outcomes of a home progressive resistance training (PRT) program augmented by neuromuscular electrical stimulation (NMES). Design Randomized controlled pilot trial. Setting Participant homes. Participants People with multiple sclerosis (MS) (N=37) who use a walking aid. Interventions A 12-week home PRT program or the same program augmented by NMES. Main Outcome Measures Strength using hand-held dynamometry; repeated sit to stand test; Berg Balance Scale; timed Up & Go test; 12-Item Multiple Sclerosis Walking Scale; Multiple Sclerosis Impact Scale-29, version 2; and Modified Fatigue Impact Scale (MFIS). The NMES group also completed a device usability questionnaire. Results Only change in MFIS score was significantly greater in the NMES group than the PRT group (P=.012). The NMES group improved significantly in quadriceps endurance (median of change, 8.5; P=.043), balance (median of change, 3.5; P=.001), physical impact of MS (median of change, -8.3; P=.001), and impact of fatigue (median of change, -17; P=.001). Participants rated the device as highly usable. Conclusions This pilot study suggests that a home PRT program with NMES is feasible, and the neuromuscular electrical stimulation device is usable by this population. Only reduction in impact of fatigue was greater in the NMES than the PRT group.
AB - Objective To investigate the feasibility and preliminary outcomes of a home progressive resistance training (PRT) program augmented by neuromuscular electrical stimulation (NMES). Design Randomized controlled pilot trial. Setting Participant homes. Participants People with multiple sclerosis (MS) (N=37) who use a walking aid. Interventions A 12-week home PRT program or the same program augmented by NMES. Main Outcome Measures Strength using hand-held dynamometry; repeated sit to stand test; Berg Balance Scale; timed Up & Go test; 12-Item Multiple Sclerosis Walking Scale; Multiple Sclerosis Impact Scale-29, version 2; and Modified Fatigue Impact Scale (MFIS). The NMES group also completed a device usability questionnaire. Results Only change in MFIS score was significantly greater in the NMES group than the PRT group (P=.012). The NMES group improved significantly in quadriceps endurance (median of change, 8.5; P=.043), balance (median of change, 3.5; P=.001), physical impact of MS (median of change, -8.3; P=.001), and impact of fatigue (median of change, -17; P=.001). Participants rated the device as highly usable. Conclusions This pilot study suggests that a home PRT program with NMES is feasible, and the neuromuscular electrical stimulation device is usable by this population. Only reduction in impact of fatigue was greater in the NMES than the PRT group.
KW - Mobility limitation
KW - Multiple sclerosis
KW - Rehabilitation
KW - Therapeutic electrical stimulation
UR - http://www.scopus.com/inward/record.url?scp=84921433147&partnerID=8YFLogxK
U2 - 10.1016/j.apmr.2014.09.021
DO - 10.1016/j.apmr.2014.09.021
M3 - Article
C2 - 25308884
AN - SCOPUS:84921433147
SN - 0003-9993
VL - 96
SP - 197
EP - 204
JO - Archives of Physical Medicine and Rehabilitation
JF - Archives of Physical Medicine and Rehabilitation
IS - 2
ER -