TY - JOUR
T1 - Poly(ethylene glycol)-salt aqueous two-phase systems with easily recyclable volatile salts
AU - Van Berlo, Mos
AU - Luyben, Karel Ch A.M.
AU - Van Der Wielen, Luuk A.M.
PY - 1998/6/26
Y1 - 1998/6/26
N2 - Aqueous two-phase systems (ATPSs) have great potential in the downstream processing of fermentation products. However, the consumption of large amounts of auxiliary materials limits application in industrial practice. Promising alternatives to the salts used so far are volatile salts such as ammonium bicarbonate and ammonium carbamate, which can be recycled to the extraction system as gaseous carbon dioxide and ammonia. In this work, it is demonstrated that ammonium carbamate in combination with poly(ethylene glycol) (PEG, molecular masses of 2000, 4000 and 10 000) indeed produces aqueous two-phase systems (ATPSs) at a temperature of 25°C and atmospheric pressure. Ammonium bicarbonate is clearly not suitable as a phase-forming salt, because of its too-low solubility in water.
AB - Aqueous two-phase systems (ATPSs) have great potential in the downstream processing of fermentation products. However, the consumption of large amounts of auxiliary materials limits application in industrial practice. Promising alternatives to the salts used so far are volatile salts such as ammonium bicarbonate and ammonium carbamate, which can be recycled to the extraction system as gaseous carbon dioxide and ammonia. In this work, it is demonstrated that ammonium carbamate in combination with poly(ethylene glycol) (PEG, molecular masses of 2000, 4000 and 10 000) indeed produces aqueous two-phase systems (ATPSs) at a temperature of 25°C and atmospheric pressure. Ammonium bicarbonate is clearly not suitable as a phase-forming salt, because of its too-low solubility in water.
KW - Ammonium carbamate
KW - Aqueous two-phase systems
KW - Volatile salts
UR - http://www.scopus.com/inward/record.url?scp=0032568903&partnerID=8YFLogxK
U2 - 10.1016/S0378-4347(97)00627-0
DO - 10.1016/S0378-4347(97)00627-0
M3 - Article
C2 - 9699975
AN - SCOPUS:0032568903
SN - 1572-6495
VL - 711
SP - 61
EP - 68
JO - Journal of Chromatography B: Biomedical Applications
JF - Journal of Chromatography B: Biomedical Applications
IS - 1-2
ER -