TY - JOUR
T1 - Polyphenols as potential antiproliferative agents
T2 - scientific trends
AU - do Carmo, Mariana Araújo Vieira
AU - Pressete, Carolina Girotto
AU - Marques, Marcos José
AU - Granato, Daniel
AU - Azevedo, Luciana
N1 - Publisher Copyright:
© 2018 Elsevier Ltd
PY - 2018/12
Y1 - 2018/12
N2 - Bioactive compounds are associated with decreased in oxidative stress, inflammation and consequently in risk of non-communicable diseases. Polyphenols have demonstrated potential biological activity in many diseases, such as cancer, diabetes, inflammation, obesity-related diseases, neurodegenerative disorders, bacterial and viral infections or cardiovascular diseases due to antioxidant and prooxidant capacities. Indeed, these compounds may still have many applications in the pharmaceutical and food industries, with potential functional properties in vivo. This review article discusses the relationship between polyphenols, their antiproliferative effects and the mechanisms involved, oxidative stress, technological applications and future perspectives in this research field.
AB - Bioactive compounds are associated with decreased in oxidative stress, inflammation and consequently in risk of non-communicable diseases. Polyphenols have demonstrated potential biological activity in many diseases, such as cancer, diabetes, inflammation, obesity-related diseases, neurodegenerative disorders, bacterial and viral infections or cardiovascular diseases due to antioxidant and prooxidant capacities. Indeed, these compounds may still have many applications in the pharmaceutical and food industries, with potential functional properties in vivo. This review article discusses the relationship between polyphenols, their antiproliferative effects and the mechanisms involved, oxidative stress, technological applications and future perspectives in this research field.
UR - http://www.scopus.com/inward/record.url?scp=85056302486&partnerID=8YFLogxK
U2 - 10.1016/j.cofs.2018.10.013
DO - 10.1016/j.cofs.2018.10.013
M3 - Review article
AN - SCOPUS:85056302486
SN - 2214-7993
VL - 24
SP - 26
EP - 35
JO - Current Opinion in Food Science
JF - Current Opinion in Food Science
ER -