Polyphenols as potential antiproliferative agents: scientific trends

Mariana Araújo Vieira do Carmo, Carolina Girotto Pressete, Marcos José Marques, Daniel Granato, Luciana Azevedo

Research output: Contribution to journalReview articlepeer-review

Abstract

Bioactive compounds are associated with decreased in oxidative stress, inflammation and consequently in risk of non-communicable diseases. Polyphenols have demonstrated potential biological activity in many diseases, such as cancer, diabetes, inflammation, obesity-related diseases, neurodegenerative disorders, bacterial and viral infections or cardiovascular diseases due to antioxidant and prooxidant capacities. Indeed, these compounds may still have many applications in the pharmaceutical and food industries, with potential functional properties in vivo. This review article discusses the relationship between polyphenols, their antiproliferative effects and the mechanisms involved, oxidative stress, technological applications and future perspectives in this research field.

Original languageEnglish
Pages (from-to)26-35
Number of pages10
JournalCurrent Opinion in Food Science
Volume24
DOIs
Publication statusPublished - Dec 2018
Externally publishedYes

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