Abstract
In the present work, cobalt ferrite nanoparticles (CoFe 2 O 4 NPs) have been synthesized by combustion method. The surface of the CoFe 2 O 4 NPs was modified with biocompatible polyvinyl alcohol (PVA). To investigate effect and nature of coating on the surface of CoFe 2 O 4 NPs, the NPs were characterized X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy and thermogravimetric analysis (TGA). The transmission electron microscopy (TEM) and dynamic light scattering (DLS) results demonstrate the monodispersed characteristics of CoFe 2 O 4 NPs after surface modification with PVA. The decrease in contact angle from 162° to 50° with PVA coating on NPs indicates the transition from hydrophobic nature to hydrophilic. The Magnetic properties measurement system (MPMS) results show that the NPs have ferromagnetic behavior with high magnetization of 75.04 and 71.02 emu/g of uncoated and coated CoFe 2 O 4 NPs respectively. These PVA coated NPs exhibit less toxicity over uncoated CoFe 2 O 4 NPs up to 1.8 mg mL -1 when tested with mouse fibroblast L929 cell line.
Original language | English |
---|---|
Pages (from-to) | 598-604 |
Number of pages | 7 |
Journal | Applied Surface Science |
Volume | 264 |
DOIs | |
Publication status | Published - 1 Jan 2013 |
Externally published | Yes |
Keywords
- Cytotoxicity
- Magnetic diameter
- Polyvinyl alcohol coatings