TY - JOUR
T1 - Potential-Modulated Surface-Enhanced Raman Spectroscopy of Tolmetin at Gold Nanoparticle Film Functionalized Polarizable Liquid-Liquid Interfaces
AU - Tarabet, Madjid
AU - Muñoz, Nataly Rey
AU - Scanlon, Micheál D.
AU - Herzog, Grégoire
AU - Dossot, Manuel
N1 - Publisher Copyright:
© 2024 The Authors. Published by American Chemical Society.
PY - 2024/5/16
Y1 - 2024/5/16
N2 - An aqueous colloidal suspension of gold nanoparticles (AuNPs) may be condensed into a thin fractal film at the polarizable liquid-liquid interface formed between two immiscible electrolyte solutions upon injection of millimolar concentrations of sodium chloride to the aqueous phase. By adjusting the interfacial polarization conditions (negative, intermediate, and positive open-circuit potentials), the morphology of the film is modified, resulting in unique surface plasmon properties of the film, which enable in situ surface-enhanced Raman spectroscopy (SERS). Intense SERS signals are observed at the polarizable liquid-liquid interface when micromolar concentrations of tolmetin, a nonsteroidal anti-inflammatory drug, are entrapped in the AuNP fractal film. The change in the signal intensity, averaged over multiple spectra, with respect to the concentration of tolmetin, depends on the polarization conditions and suggests the presence of chemical-induced damping effects on the surface plasmons of the gold film.
AB - An aqueous colloidal suspension of gold nanoparticles (AuNPs) may be condensed into a thin fractal film at the polarizable liquid-liquid interface formed between two immiscible electrolyte solutions upon injection of millimolar concentrations of sodium chloride to the aqueous phase. By adjusting the interfacial polarization conditions (negative, intermediate, and positive open-circuit potentials), the morphology of the film is modified, resulting in unique surface plasmon properties of the film, which enable in situ surface-enhanced Raman spectroscopy (SERS). Intense SERS signals are observed at the polarizable liquid-liquid interface when micromolar concentrations of tolmetin, a nonsteroidal anti-inflammatory drug, are entrapped in the AuNP fractal film. The change in the signal intensity, averaged over multiple spectra, with respect to the concentration of tolmetin, depends on the polarization conditions and suggests the presence of chemical-induced damping effects on the surface plasmons of the gold film.
UR - http://www.scopus.com/inward/record.url?scp=85192337416&partnerID=8YFLogxK
U2 - 10.1021/acs.jpcc.4c00937
DO - 10.1021/acs.jpcc.4c00937
M3 - Article
AN - SCOPUS:85192337416
SN - 1932-7447
VL - 128
SP - 7936
EP - 7947
JO - Journal of Physical Chemistry C
JF - Journal of Physical Chemistry C
IS - 19
ER -