Primary jejunoileal tumors: A review of 45 cases

L. A.J. Desa, J. Bridger, P. A. Grace, T. Krausz, J. Spencer

Research output: Contribution to journalReview articlepeer-review

Abstract

We reviewed 45 patients who underwent surgery for primary jejunoileal tumors over a 15-year period. There were 16 benign and 29 malignant tumors, which included 13 lymphomas, 7 adenocarcinomas, 7 carcinoid tumors, and 2 leiomyosarcomas. Eighteen patients, 13 of whom had benign tumors, presented with intestinal bleeding and 5 tumors were found incidentally at laparotomy. Benign lesions were more frequently sited in the jejunum while malignant lesions were more common in the ileum (p<0.001). Lesions presenting with hemorrhage were more likely to be benign than malignant (p<0.001) and were more commonly sited in the jejunum than in the ileum (p<0.05). Visceral perforation (31%), intestinal obstruction (21%), and an abdominal mass (17%) were other presenting features in patients with malignant tumors. In spite of a wide variety of investigations, the correct diagnosis was reached preoperatively in only 31% of patients. Surgical management included either limited bowel resection or segmental resection with regional lymphadenectomy. Operative mortality was 13% and morbidity was 36%. Actuarial 5-year survival for all malignant tumors was 24%, being 64% at 5 years for carcinoid tumors, 20% at 30 months for adenocarcinomas, and 10% at 42 months for lymphomas. These results reemphasize the need for a high index of suspicion and early laparotomy in patients with obscure intestinal symptoms if the prognosis of small bowel tumors is to improve.

Original languageEnglish
Pages (from-to)81-86
Number of pages6
JournalWorld Journal of Surgery
Volume15
Issue number1
DOIs
Publication statusPublished - Jan 1991
Externally publishedYes

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