Probiotics: Towards demonstrating efficacy

T. Mattila-Sandholm; S. Blum; J. K. Collins; R. Crittenden; W. De Vos; C. Dunne; R. Fondén; G. Grenov; E. Isolauri; B. Kiely; P. Marteau; L. Morelli; A. Ouwehand; R. Reniero; M. Saarela; S. Salminen; M. Saxelin; E. Schiffrin; F. Shanahan; E. Vaughan; A. Von Wright

doi:10.1016/S0924-2244(00)00029-7

Probiotics: Towards demonstrating efficacy

T. Mattila-Sandholm
, S. Blum
, J. K. Collins
, R. Crittenden
, W. De Vos
, C. Dunne
, R. Fondén
, G. Grenov
, E. Isolauri
, B. Kiely
, P. Marteau
, L. Morelli
, A. Ouwehand
, R. Reniero
, M. Saarela
, S. Salminen
, M. Saxelin
, E. Schiffrin
, F. Shanahan
, E. Vaughan

A. Von Wright

VTT Technical Research Centre of Finland Ltd.
Nestle
University College Cork
Wageningen University & Research
Arla Foods
Chr. Hansen AS
European Hospital
University of Turku
Catholic University of the Sacred Heart
Valio Ltd.
University of Eastern Finland

Research output: Contribution to journal › Article › peer-review

Abstract

PROBDEMO, a multi-centre European research project, began in 1996 with the aim of demonstrating that probiotic micro-organisms can positively effect human health in rigorously conducted human clinical studies. These studies, now completed, have shown that some probiotics can influence the composition of the intestinal microbiota and modulate the host immune system with measurable benefits to health, including the control of atopic eczema in infants with food allergy. Considerable promise was also demonstrated for the use of selected probiotics in controlling inflammatory bowel disease, and infections in children and the elderly. The scientific approaches to selecting and evaluating probiotics that were demonstrated in the PROBDEMO project provide a model for food manufacturers to move further towards demonstrating efficacy for their probiotic products. (C) 2000 Elsevier Science Ltd.

Original language	English
Pages (from-to)	393-399
Number of pages	7
Journal	Trends in Food Science and Technology
Volume	10
Issue number	12
DOIs	https://doi.org/10.1016/S0924-2244(00)00029-7
Publication status	Published - 1999
Externally published	Yes

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Mattila-Sandholm, T., Blum, S., Collins, J. K., Crittenden, R., De Vos, W., Dunne, C., Fondén, R., Grenov, G., Isolauri, E., Kiely, B., Marteau, P., Morelli, L., Ouwehand, A., Reniero, R., Saarela, M., Salminen, S., Saxelin, M., Schiffrin, E., Shanahan, F., ... Von Wright, A. (1999). Probiotics: Towards demonstrating efficacy. Trends in Food Science and Technology, 10(12), 393-399. https://doi.org/10.1016/S0924-2244(00)00029-7

@article{ace47ae9813d42a9a5726fa467080549,

title = "Probiotics: Towards demonstrating efficacy",

abstract = "PROBDEMO, a multi-centre European research project, began in 1996 with the aim of demonstrating that probiotic micro-organisms can positively effect human health in rigorously conducted human clinical studies. These studies, now completed, have shown that some probiotics can influence the composition of the intestinal microbiota and modulate the host immune system with measurable benefits to health, including the control of atopic eczema in infants with food allergy. Considerable promise was also demonstrated for the use of selected probiotics in controlling inflammatory bowel disease, and infections in children and the elderly. The scientific approaches to selecting and evaluating probiotics that were demonstrated in the PROBDEMO project provide a model for food manufacturers to move further towards demonstrating efficacy for their probiotic products. (C) 2000 Elsevier Science Ltd.",

author = "T. Mattila-Sandholm and S. Blum and Collins, \{J. K.\} and R. Crittenden and \{De Vos\}, W. and C. Dunne and R. Fond{\'e}n and G. Grenov and E. Isolauri and B. Kiely and P. Marteau and L. Morelli and A. Ouwehand and R. Reniero and M. Saarela and S. Salminen and M. Saxelin and E. Schiffrin and F. Shanahan and E. Vaughan and \{Von Wright\}, A.",

year = "1999",

doi = "10.1016/S0924-2244(00)00029-7",

language = "English",

volume = "10",

pages = "393--399",

journal = "Trends in Food Science and Technology",

issn = "0924-2244",

number = "12",

}

Mattila-Sandholm, T, Blum, S, Collins, JK, Crittenden, R, De Vos, W, Dunne, C, Fondén, R, Grenov, G, Isolauri, E, Kiely, B, Marteau, P, Morelli, L, Ouwehand, A, Reniero, R, Saarela, M, Salminen, S, Saxelin, M, Schiffrin, E, Shanahan, F, Vaughan, E & Von Wright, A 1999, 'Probiotics: Towards demonstrating efficacy', Trends in Food Science and Technology, vol. 10, no. 12, pp. 393-399. https://doi.org/10.1016/S0924-2244(00)00029-7

TY - JOUR

T1 - Probiotics

T2 - Towards demonstrating efficacy

AU - Mattila-Sandholm, T.

AU - Blum, S.

AU - Collins, J. K.

AU - Crittenden, R.

AU - De Vos, W.

AU - Dunne, C.

AU - Fondén, R.

AU - Grenov, G.

AU - Isolauri, E.

AU - Kiely, B.

AU - Marteau, P.

AU - Morelli, L.

AU - Ouwehand, A.

AU - Reniero, R.

AU - Saarela, M.

AU - Salminen, S.

AU - Saxelin, M.

AU - Schiffrin, E.

AU - Shanahan, F.

AU - Vaughan, E.

AU - Von Wright, A.

PY - 1999

Y1 - 1999

N2 - PROBDEMO, a multi-centre European research project, began in 1996 with the aim of demonstrating that probiotic micro-organisms can positively effect human health in rigorously conducted human clinical studies. These studies, now completed, have shown that some probiotics can influence the composition of the intestinal microbiota and modulate the host immune system with measurable benefits to health, including the control of atopic eczema in infants with food allergy. Considerable promise was also demonstrated for the use of selected probiotics in controlling inflammatory bowel disease, and infections in children and the elderly. The scientific approaches to selecting and evaluating probiotics that were demonstrated in the PROBDEMO project provide a model for food manufacturers to move further towards demonstrating efficacy for their probiotic products. (C) 2000 Elsevier Science Ltd.

AB - PROBDEMO, a multi-centre European research project, began in 1996 with the aim of demonstrating that probiotic micro-organisms can positively effect human health in rigorously conducted human clinical studies. These studies, now completed, have shown that some probiotics can influence the composition of the intestinal microbiota and modulate the host immune system with measurable benefits to health, including the control of atopic eczema in infants with food allergy. Considerable promise was also demonstrated for the use of selected probiotics in controlling inflammatory bowel disease, and infections in children and the elderly. The scientific approaches to selecting and evaluating probiotics that were demonstrated in the PROBDEMO project provide a model for food manufacturers to move further towards demonstrating efficacy for their probiotic products. (C) 2000 Elsevier Science Ltd.

UR - https://www.scopus.com/pages/publications/0033304276

U2 - 10.1016/S0924-2244(00)00029-7

DO - 10.1016/S0924-2244(00)00029-7

M3 - Article

AN - SCOPUS:0033304276

SN - 0924-2244

VL - 10

SP - 393

EP - 399

JO - Trends in Food Science and Technology

JF - Trends in Food Science and Technology

IS - 12

ER -

Probiotics: Towards demonstrating efficacy

Abstract

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