TY - JOUR
T1 - Progress and promise of alternative animal and non-animal methods in biomedical research
AU - Freires, Irlan Almeida
AU - Morelo, David Fernando Colon
AU - Soares, Lélio Fernando Ferreira
AU - Costa, Isabela Silva
AU - de Araújo, Leonardo Pereira
AU - Breseghello, Isadora
AU - Abdalla, Henrique Ballassini
AU - Lazarini, Josy Goldoni
AU - Rosalen, Pedro Luiz
AU - Pigossi, Suzane Cristina
AU - Franchin, Marcelo
N1 - Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2023/9
Y1 - 2023/9
N2 - Cell culture and invertebrate animal models reflect a significant evolution in scientific research by providing reliable evidence on the physiopathology of diseases, screening for new drugs, and toxicological tests while reducing the need for mammals. In this review, we discuss the progress and promise of alternative animal and non-animal methods in biomedical research, with a special focus on drug toxicity.
AB - Cell culture and invertebrate animal models reflect a significant evolution in scientific research by providing reliable evidence on the physiopathology of diseases, screening for new drugs, and toxicological tests while reducing the need for mammals. In this review, we discuss the progress and promise of alternative animal and non-animal methods in biomedical research, with a special focus on drug toxicity.
UR - http://dx.doi.org/10.1007/s00204-023-03532-1
U2 - 10.1007/s00204-023-03532-1
DO - 10.1007/s00204-023-03532-1
M3 - Article
SN - 0340-5761
VL - 97
SP - 2329
EP - 2342
JO - Archives of Toxicology
JF - Archives of Toxicology
IS - 9
ER -