RamiGO: An R/Bioconductor package providing an AmiGO Visualize interface

Markus S. Schröder, Daniel Gusenleitner, John Quackenbush, Aedín C. Culhane, Benjamin Haibe-Kains

Research output: Contribution to journalArticlepeer-review

Abstract

Summary: The R/Bioconductor package RamiGO is an R interface to AmiGO that enables visualization of Gene Ontology (GO) trees. Given a list of GO terms, RamiGO uses the AmiGO visualize API to import Graphviz-DOT format files into R, and export these either as images (SVG, PNG) or into Cytoscape for extended network analyses. RamiGO provides easy customization of annotation, highlighting of specific GO terms, colouring of terms by P-value or export of a simplified summary GO tree. We illustrate RamiGO functionalities in a genome-wide gene set analysis of prognostic genes in breast cancer.Availability and implementation: RamiGO is provided in R/Bioconductor, is open source under the Artistic-2.0 License and is available with a user manual containing installation, operating instructions and tutorials. It requires R version 2.15.0 or higher. URL: http://bioconductor.org/packages/release/bioc/html/RamiGO.htmlContact: Supplementary information: Supplementary data are available at Bioinformatics online.

Original languageEnglish
Pages (from-to)666-668
Number of pages3
JournalBioinformatics
Volume29
Issue number5
DOIs
Publication statusPublished - Mar 2013
Externally publishedYes

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