TY - JOUR
T1 - Separation of Trimethoxybenzene Isomers by Bile Acids
AU - Bouanga Boudiombo, Jacky S.
AU - Su, Hong
AU - Bourne, Susan A.
AU - Nassimbeni, Luigi R.
N1 - Publisher Copyright:
© 2017 American Chemical Society.
PY - 2018/1/3
Y1 - 2018/1/3
N2 - Cholic acid (CA) and deoxycholic acid (DCA) have been employed to separate the three isomers of trimethoxybenzene (TMB). The selectivity preference is CA: TMB135 > TMB123 ≈ TMB124, while it is reversed for DCA: TMB123 > TMB124 > TMB135. Some of the crystal structures with CA as host suffered from partial disorder, while the DCA structures were grown from pairs of equimolar guest mixtures, and all contained both guests in different proportions. Packing analysis revealed the importance of layering of the hydrophilic and lipophilic regions of the structures with the TMB guests accommodated in the lipophilic layers.
AB - Cholic acid (CA) and deoxycholic acid (DCA) have been employed to separate the three isomers of trimethoxybenzene (TMB). The selectivity preference is CA: TMB135 > TMB123 ≈ TMB124, while it is reversed for DCA: TMB123 > TMB124 > TMB135. Some of the crystal structures with CA as host suffered from partial disorder, while the DCA structures were grown from pairs of equimolar guest mixtures, and all contained both guests in different proportions. Packing analysis revealed the importance of layering of the hydrophilic and lipophilic regions of the structures with the TMB guests accommodated in the lipophilic layers.
UR - http://www.scopus.com/inward/record.url?scp=85040162661&partnerID=8YFLogxK
U2 - 10.1021/acs.cgd.7b01423
DO - 10.1021/acs.cgd.7b01423
M3 - Article
AN - SCOPUS:85040162661
SN - 1528-7483
VL - 18
SP - 424
EP - 430
JO - Crystal Growth and Design
JF - Crystal Growth and Design
IS - 1
ER -