Abstract
The solubility of paracetamol (4-hydroxyacetanilide) in binary mixtures of acetone + water and acetone + toluene and in ternary mixtures of water + acetone + toluene is reported. The temperature range is -5 to +30°C. In acetone + water the solubility increases to a maximum at approximately 25 mass % water before decreasing to a much lower value in pure water as compared to pure acetone. In acetone + toluene the solubility decreases monotonically with increasing toluene concentration. The water content has a strong influence also in ternary mixtures. Activity coefficients in the saturated solutions are estimated.
| Original language | English |
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| Pages (from-to) | 478-483 |
| Number of pages | 6 |
| Journal | Journal of Chemical and Engineering Data |
| Volume | 45 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - May 2000 |