Strengths and Limitations of Translating the Hybrid Nanostructures to the Clinic

This chapter aims to identify gaps in our understanding of current strengths of hybrid nanostructures in theranostics to fulfill its promise in prolonging patient survival, and to offer an overview of our current grasp of the preclinical and clinical stages of nanostructures in cancer. The chapter starts with a brief discussion of the current clinical and preclinical stages of hybrid nanostructures. Subsequently, we provide a comprehensive compilation of recent representative studies in this field, which is organized depending on the proposed clinical applications. We focus on the integration of organic–inorganic interfaces for the development of cancer therapies based on hybrid nanostructures.