Sulfoximidation of Aryl Alkenes via Oxidative C-C Bond Cleavage

KI−mediated cross-coupling between aryl alkenes and NH−sulfoximines under base- and metal-free reaction conditions has been developed. This process involves the sequential oxidative cleavage of the C-C double bond, followed by C-N bond formation to synthesize biologically relevant N-acyl sulfoximines. This protocol features a broad substrate scope, excellent functional group compatibility, and high yields. Mechanistic investigations indicate the intermediacy of benzaldehyde-derived as an acyl radical and highlight the crucial role of atmospheric oxygen as the oxygen source.