Synthesis of functionalized Co0.5Zn0.5Fe2O4 nanoparticles for biomedical applications

R. A. Bohara; H. M. Yadav; N. D. Thorat; S. S. Mali; C. K. Hong; S. G. Nanaware; S. H. Pawar

doi:10.1016/j.jmmm.2014.11.063

Synthesis of functionalized Co_0.5Zn_0.5Fe₂O₄ nanoparticles for biomedical applications

R. A. Bohara, H. M. Yadav, N. D. Thorat, S. S. Mali, C. K. Hong, S. G. Nanaware, S. H. Pawar

Research output: Contribution to journal › Article › peer-review

Abstract

In this paper, we report a simple one step method for the synthesis of uniform, water dispersible amine functionalized Co_0.5Zn_0.5Fe₂O₄ nanoparticles (AF-CZF) of size about 6 nm. The synthesis process was accomplished by refluxing Fe(acac)₃, Co(acac)₂ and Zn(acac)₂ in diethylene glycol and ethanolamine. The magnetic nanoparticles were characterized by XRD, TGDTA, FTIR, SEM and TEM techniques. Their magnetic properties were also studied by using SQUID. The synthesized particles show superparamagnetism at room temperature. AF-CZF nanoparticles exhibit good cell viability, which is above 95% at a concentration of 80 μg mL^-1 on MCF7 cell line. The AF-CZF can be a new versatile platform for many interesting biomedical applications.

Original language	English
Pages (from-to)	397-401
Number of pages	5
Journal	Journal of Magnetism and Magnetic Materials
Volume	378
DOIs	https://doi.org/10.1016/j.jmmm.2014.11.063
Publication status	Published - 15 Mar 2015
Externally published	Yes

Keywords

Amine functionalization
Biocompatibility
Magnetic nanoparticles
Superparamagnetic

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10.1016/j.jmmm.2014.11.063

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title = "Synthesis of functionalized Co0.5Zn0.5Fe2O4 nanoparticles for biomedical applications",

abstract = "In this paper, we report a simple one step method for the synthesis of uniform, water dispersible amine functionalized Co0.5Zn0.5Fe2O4 nanoparticles (AF-CZF) of size about 6 nm. The synthesis process was accomplished by refluxing Fe(acac)3, Co(acac)2 and Zn(acac)2 in diethylene glycol and ethanolamine. The magnetic nanoparticles were characterized by XRD, TGDTA, FTIR, SEM and TEM techniques. Their magnetic properties were also studied by using SQUID. The synthesized particles show superparamagnetism at room temperature. AF-CZF nanoparticles exhibit good cell viability, which is above 95% at a concentration of 80 μg mL-1 on MCF7 cell line. The AF-CZF can be a new versatile platform for many interesting biomedical applications.",

keywords = "Amine functionalization, Biocompatibility, Magnetic nanoparticles, Superparamagnetic",

author = "Bohara, {R. A.} and Yadav, {H. M.} and Thorat, {N. D.} and Mali, {S. S.} and Hong, {C. K.} and Nanaware, {S. G.} and Pawar, {S. H.}",

year = "2015",

month = mar,

day = "15",

doi = "10.1016/j.jmmm.2014.11.063",

language = "English",

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journal = "Journal of Magnetism and Magnetic Materials",

issn = "0304-8853",

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T1 - Synthesis of functionalized Co0.5Zn0.5Fe2O4 nanoparticles for biomedical applications

AU - Bohara, R. A.

AU - Yadav, H. M.

AU - Thorat, N. D.

AU - Mali, S. S.

AU - Hong, C. K.

AU - Nanaware, S. G.

AU - Pawar, S. H.

PY - 2015/3/15

Y1 - 2015/3/15

N2 - In this paper, we report a simple one step method for the synthesis of uniform, water dispersible amine functionalized Co0.5Zn0.5Fe2O4 nanoparticles (AF-CZF) of size about 6 nm. The synthesis process was accomplished by refluxing Fe(acac)3, Co(acac)2 and Zn(acac)2 in diethylene glycol and ethanolamine. The magnetic nanoparticles were characterized by XRD, TGDTA, FTIR, SEM and TEM techniques. Their magnetic properties were also studied by using SQUID. The synthesized particles show superparamagnetism at room temperature. AF-CZF nanoparticles exhibit good cell viability, which is above 95% at a concentration of 80 μg mL-1 on MCF7 cell line. The AF-CZF can be a new versatile platform for many interesting biomedical applications.

AB - In this paper, we report a simple one step method for the synthesis of uniform, water dispersible amine functionalized Co0.5Zn0.5Fe2O4 nanoparticles (AF-CZF) of size about 6 nm. The synthesis process was accomplished by refluxing Fe(acac)3, Co(acac)2 and Zn(acac)2 in diethylene glycol and ethanolamine. The magnetic nanoparticles were characterized by XRD, TGDTA, FTIR, SEM and TEM techniques. Their magnetic properties were also studied by using SQUID. The synthesized particles show superparamagnetism at room temperature. AF-CZF nanoparticles exhibit good cell viability, which is above 95% at a concentration of 80 μg mL-1 on MCF7 cell line. The AF-CZF can be a new versatile platform for many interesting biomedical applications.

KW - Amine functionalization

KW - Biocompatibility

KW - Magnetic nanoparticles

KW - Superparamagnetic

UR - http://www.scopus.com/inward/record.url?scp=84913558305&partnerID=8YFLogxK

U2 - 10.1016/j.jmmm.2014.11.063

DO - 10.1016/j.jmmm.2014.11.063

M3 - Article

AN - SCOPUS:84913558305

SN - 0304-8853

VL - 378

SP - 397

EP - 401

JO - Journal of Magnetism and Magnetic Materials

JF - Journal of Magnetism and Magnetic Materials

ER -

Synthesis of functionalized Co_0.5Zn_0.5Fe₂O₄ nanoparticles for biomedical applications

Abstract

Keywords

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