TY - JOUR
T1 - Techno-economic analysis of succinic acid production using adsorption from fermentation medium
AU - Efe, Çaǧri
AU - van der Wielen, Luuk A.M.
AU - Straathof, Adrie J.J.
PY - 2013/9
Y1 - 2013/9
N2 - Fermentation of renewable resources is becoming increasingly attractive for production of C4 bulk chemicals. One interesting C4 building block is succinic acid. This study presents a conceptual design of a process for succinic acid production. The process begins with aerobic fermentation using a hypothetical Saccharomyces cerevisiae strain at pH 4. After centrifugation the broth is sent to adsorption. A ZSM-5 zeolite is used to preferentially adsorb succinic acid. Desorption is performed using hot water. This water is then flashed off, and succinic acid is crystallized and dried. The plant capacity is set to 30kta-1 according to the projected demand. Cane sugar is the selected feedstock. The calculated selling price of succinic acid is 2.26$kg-1 with the potential to decrease to values as low as 1$kg-1. Major recommendations include experimental investigation of the feasibility of the metabolic engineering of the S. cerevisiae strain, of the fermentation parameters, of the crystallization, and of the process integration.
AB - Fermentation of renewable resources is becoming increasingly attractive for production of C4 bulk chemicals. One interesting C4 building block is succinic acid. This study presents a conceptual design of a process for succinic acid production. The process begins with aerobic fermentation using a hypothetical Saccharomyces cerevisiae strain at pH 4. After centrifugation the broth is sent to adsorption. A ZSM-5 zeolite is used to preferentially adsorb succinic acid. Desorption is performed using hot water. This water is then flashed off, and succinic acid is crystallized and dried. The plant capacity is set to 30kta-1 according to the projected demand. Cane sugar is the selected feedstock. The calculated selling price of succinic acid is 2.26$kg-1 with the potential to decrease to values as low as 1$kg-1. Major recommendations include experimental investigation of the feasibility of the metabolic engineering of the S. cerevisiae strain, of the fermentation parameters, of the crystallization, and of the process integration.
KW - Adsorption
KW - Fermentation
KW - Process analysis
KW - Production cost
KW - Succinic acid
KW - Zeolite
UR - http://www.scopus.com/inward/record.url?scp=84880177004&partnerID=8YFLogxK
U2 - 10.1016/j.biombioe.2013.06.002
DO - 10.1016/j.biombioe.2013.06.002
M3 - Article
AN - SCOPUS:84880177004
SN - 0961-9534
VL - 56
SP - 479
EP - 492
JO - Biomass and Bioenergy
JF - Biomass and Bioenergy
ER -