TY - JOUR
T1 - The direct and indirect effects of bioactive compounds against coronavirus
AU - Tomas, Merve
AU - Capanoglu, Esra
AU - Bahrami, Akbar
AU - Hosseini, Hamed
AU - Akbari-Alavijeh, Safoura
AU - Shaddel, Rezvan
AU - Rehman, Abdur
AU - Rezaei, Atefe
AU - Rashidinejad, Ali
AU - Garavand, Farhad
AU - Goudarzi, Mostafa
AU - Jafari, Seid Mahdi
N1 - Publisher Copyright:
© 2021 The Authors. Food Frontiers published by John Wiley & Sons Australia, Ltd and Nanchang University, Northwest University, Jiangsu University, Zhejiang University, Fujian Agriculture and Forestry University.
PY - 2022/3
Y1 - 2022/3
N2 - Emerging viruses are known to pose a threat to humans in the world. COVID-19, a newly emerging viral respiratory disease, can spread quickly from people to people via respiratory droplets, cough, sneeze, or exhale. Up to now, there are no specific therapies found for the treatment of COVID-19. In this sense, the rising demand for effective antiviral drugs is stressed. The main goal of the present study is to cover the current literature about bioactive compounds (e.g., polyphenols, glucosinolates, carotenoids, minerals, vitamins, oligosaccharides, bioactive peptides, essential oils, and probiotics) with potential efficiency against COVID-19, showing antiviral activities via the inhibition of coronavirus entry into the host cell, coronavirus enzymes, as well as the virus replication in human cells. In turn, these compounds can boost the immune system, helping fight against COVID-19. Overall, it can be concluded that bioactives and the functional foods containing these compounds can be natural alternatives for boosting the immune system and defeating coronavirus.
AB - Emerging viruses are known to pose a threat to humans in the world. COVID-19, a newly emerging viral respiratory disease, can spread quickly from people to people via respiratory droplets, cough, sneeze, or exhale. Up to now, there are no specific therapies found for the treatment of COVID-19. In this sense, the rising demand for effective antiviral drugs is stressed. The main goal of the present study is to cover the current literature about bioactive compounds (e.g., polyphenols, glucosinolates, carotenoids, minerals, vitamins, oligosaccharides, bioactive peptides, essential oils, and probiotics) with potential efficiency against COVID-19, showing antiviral activities via the inhibition of coronavirus entry into the host cell, coronavirus enzymes, as well as the virus replication in human cells. In turn, these compounds can boost the immune system, helping fight against COVID-19. Overall, it can be concluded that bioactives and the functional foods containing these compounds can be natural alternatives for boosting the immune system and defeating coronavirus.
KW - antiviral activity
KW - bioactive compounds
KW - coronavirus
KW - COVID-19
KW - functional foods
KW - immune system
UR - http://www.scopus.com/inward/record.url?scp=85129109523&partnerID=8YFLogxK
U2 - 10.1002/fft2.119
DO - 10.1002/fft2.119
M3 - Review article
AN - SCOPUS:85129109523
SN - 2643-8429
VL - 3
SP - 96
EP - 123
JO - Food Frontiers
JF - Food Frontiers
IS - 1
ER -
