The Epstein-Barr virus and its association with human cancers

K. R.N. Baumforth, L. S. Young, K. J. Flavell, C. Constandinou, P. G. Murray

Research output: Contribution to journalReview articlepeer-review

Abstract

The Epstein-Barr virus (EBV) has been linked to the development of a variety of human malignancies, including Burkitt's lymphoma, Hodgkin's disease, nasopharyngeal carcinoma, some T cell lymphomas, post-transplant lymphoproliferative disease, and more recently, certain cancers of the stomach and smooth muscle. This review summarises these associations and in particular the role of the viral latent genes in the transformation process.

Original languageEnglish
Pages (from-to)307-322
Number of pages16
JournalJournal of Clinical Pathology - Molecular Pathology
Volume52
Issue number6
DOIs
Publication statusPublished - 1999
Externally publishedYes

Keywords

  • Burkitt's lymphoma
  • Epstein-Barr virus
  • Hodgkin's disease
  • Nasopharyngeal carcinoma
  • Post-transplant lymphoproliferative disease
  • T cell lymphoma

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