The no-reflow phenomenon in the coronary circulation

Thomas J. Kiernan; Nicholas J. Ruggiero; Juan M. Bernal; Creighton W. Don; Christian Witzke; Gareth D. Kiernan; Roberto J. Cubeddu; Bryan P. Yan

doi:10.2174/187152509789105426

The no-reflow phenomenon in the coronary circulation

Thomas J. Kiernan, Nicholas J. Ruggiero, Juan M. Bernal, Creighton W. Don, Christian Witzke, Gareth D. Kiernan, Roberto J. Cubeddu, Bryan P. Yan

Research output: Contribution to journal › Review article › peer-review

Abstract

The no-reflow phenomenon is a poorly understood complication of percutaneous coronary intervention in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion from the epicardial coronary artery or arteries. In this contemporary review we endeavour to discuss the pathophysiology of coronary no-reflow, understand the predictors and describe current pharmacological and mechanical strategies to prevent and treat coronary no-reflow.

Original language	English
Pages (from-to)	181-192
Number of pages	12
Journal	Cardiovascular and Hematological Agents in Medicinal Chemistry
Volume	7
Issue number	3
DOIs	https://doi.org/10.2174/187152509789105426
Publication status	Published - 2009
Externally published	Yes

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10.2174/187152509789105426

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title = "The no-reflow phenomenon in the coronary circulation",

abstract = "The no-reflow phenomenon is a poorly understood complication of percutaneous coronary intervention in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion from the epicardial coronary artery or arteries. In this contemporary review we endeavour to discuss the pathophysiology of coronary no-reflow, understand the predictors and describe current pharmacological and mechanical strategies to prevent and treat coronary no-reflow.",

author = "Kiernan, {Thomas J.} and Ruggiero, {Nicholas J.} and Bernal, {Juan M.} and Don, {Creighton W.} and Christian Witzke and Kiernan, {Gareth D.} and Cubeddu, {Roberto J.} and Yan, {Bryan P.}",

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AU - Kiernan, Thomas J.

AU - Ruggiero, Nicholas J.

AU - Bernal, Juan M.

AU - Don, Creighton W.

AU - Witzke, Christian

AU - Kiernan, Gareth D.

AU - Cubeddu, Roberto J.

AU - Yan, Bryan P.

PY - 2009

Y1 - 2009

N2 - The no-reflow phenomenon is a poorly understood complication of percutaneous coronary intervention in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion from the epicardial coronary artery or arteries. In this contemporary review we endeavour to discuss the pathophysiology of coronary no-reflow, understand the predictors and describe current pharmacological and mechanical strategies to prevent and treat coronary no-reflow.

AB - The no-reflow phenomenon is a poorly understood complication of percutaneous coronary intervention in which diminished blood flow to distal microvascular beds persists despite the successful treatment of the occlusive lesion from the epicardial coronary artery or arteries. In this contemporary review we endeavour to discuss the pathophysiology of coronary no-reflow, understand the predictors and describe current pharmacological and mechanical strategies to prevent and treat coronary no-reflow.

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DO - 10.2174/187152509789105426

M3 - Review article

C2 - 19689256

AN - SCOPUS:70349511904

SN - 1871-5257

VL - 7

SP - 181

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JO - Cardiovascular and Hematological Agents in Medicinal Chemistry

JF - Cardiovascular and Hematological Agents in Medicinal Chemistry

IS - 3

ER -

The no-reflow phenomenon in the coronary circulation

Abstract

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