The Role of Hyaluronic Acid in Tissue Engineering

Maurice N. Collins; Fernanda Zamboni; Aleksandra Serafin; Guang Ren; A. V. Thanusha; Mario Culebras

doi:10.1007/978-3-030-42215-8_56

The Role of Hyaluronic Acid in Tissue Engineering

Maurice N. Collins, Fernanda Zamboni, Aleksandra Serafin, Guang Ren, A. V. Thanusha, Mario Culebras

School of Engineering

University of Limerick

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Hyaluronic acid (HA) is a glycosaminoglycan that is found in extracellular tissue in many parts of the body. It is a material of increasing importance to biomaterial science and is finding applications in diverse areas ranging from tissue culture scaffolds to cosmetic materials. This chapter considers the recent research on the role of HA in tissue engineering and the importance of HA as an immunomodulatory material. The chemical modifications and processing methods employed to produce HA-modified tissue scaffolds are discussed, thus giving a better understanding of the structure-function-property relationships that influence scaffold performance, tissue growth, and regeneration. The chapter concludes with a vision for the future of HA in tissue-engineered constructs.

Original language	English
Title of host publication	Polysaccharides of Microbial Origin
Subtitle of host publication	Biomedical Applications: With 257 Figures and 85 Tables
Publisher	Springer International Publishing
Pages	1063-1116
Number of pages	54
ISBN (Electronic)	9783030422158
ISBN (Print)	9783030422141
DOIs	https://doi.org/10.1007/978-3-030-42215-8_56
Publication status	Published - 1 Jan 2022

Keywords

Antimicrobial
Chemical modification
Hyaluronic acid
Immunomodulatory
Scaffolds
Tissue engineering
Vascularization

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10.1007/978-3-030-42215-8_56

Cite this

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AU - Ren, Guang

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KW - Vascularization

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The Role of Hyaluronic Acid in Tissue Engineering

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Keywords

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