TY - JOUR
T1 - The role of mesenteric organ in inflammatory bowel disease
T2 - far more than originally proposed
AU - Li, Yi
AU - Coffey, John Calvin
N1 - Publisher Copyright:
Copyright © 2019 by the Chinese Medical Association.
PY - 2019/10/25
Y1 - 2019/10/25
N2 - It has been recently recognized the mesentery as a single anatomical and structural unit with functional properties that plays a role in both physiological and pathological mechanisms of inflammatory bowel disease (IBD). Components of mesentery including adipose tissue, lymphatics, verves, and vesicular are especially implicated in the pathogenesis and disease progress of Crohn's disease. Mesentery and inflammatory bowel disease has several relevant aspects, including diagnosis, disease phenotype, disease severity, extent of lesion, medical therapy and surgical resection. Whether mesenteric lesionsare the cause or consequence of inflamed bowel is debatable. The mesentery may be therapeutically targeted by pharmacological and operative intervention and possibly change the disease progress and outcomes of IBD.
AB - It has been recently recognized the mesentery as a single anatomical and structural unit with functional properties that plays a role in both physiological and pathological mechanisms of inflammatory bowel disease (IBD). Components of mesentery including adipose tissue, lymphatics, verves, and vesicular are especially implicated in the pathogenesis and disease progress of Crohn's disease. Mesentery and inflammatory bowel disease has several relevant aspects, including diagnosis, disease phenotype, disease severity, extent of lesion, medical therapy and surgical resection. Whether mesenteric lesionsare the cause or consequence of inflamed bowel is debatable. The mesentery may be therapeutically targeted by pharmacological and operative intervention and possibly change the disease progress and outcomes of IBD.
KW - Crohn's disease
KW - Inflammatory bowel disease
KW - Mesenteric organ
KW - Mesentery
UR - http://www.scopus.com/inward/record.url?scp=85099944957&partnerID=8YFLogxK
U2 - 10.3760/cma.j.issn.2096-367X.2019.04.002
DO - 10.3760/cma.j.issn.2096-367X.2019.04.002
M3 - Article
AN - SCOPUS:85099944957
SN - 2096-367X
VL - 3
SP - 280
EP - 283
JO - Chinese Journal of Inflammatory Bowel Diseases
JF - Chinese Journal of Inflammatory Bowel Diseases
IS - 4
ER -