TY - JOUR
T1 - The structure of the hyponitrite species in a heme Fe-Cu binuclear center
AU - Varotsis, Constantinos
AU - Ohta, Takehiro
AU - Kitagawa, Teizo
AU - Soulimane, Tewfik
AU - Pinakoulaki, Eftychia
PY - 2007
Y1 - 2007
N2 - NO laughing matter: The enzymatic production of laughing gas (N 2O) from two molecules of NO requires the formation of the N-N bond and the subsequent cleavage of the N-OH bond. Resonance Raman spectroscopic studies have now provided evidence for the formation of the key intermediate, the hyponitrite species (see the optimized molecular structure), in the heme a3 Fe-CuB binuclear center of ba3- oxidoreductase from Thermus thermophilus. (Figure Presented).
AB - NO laughing matter: The enzymatic production of laughing gas (N 2O) from two molecules of NO requires the formation of the N-N bond and the subsequent cleavage of the N-OH bond. Resonance Raman spectroscopic studies have now provided evidence for the formation of the key intermediate, the hyponitrite species (see the optimized molecular structure), in the heme a3 Fe-CuB binuclear center of ba3- oxidoreductase from Thermus thermophilus. (Figure Presented).
KW - Enzymes
KW - Metalloenzymes
KW - Nitrogen oxides
KW - Raman spectroscopy
KW - Structure elucidation
UR - http://www.scopus.com/inward/record.url?scp=34250374882&partnerID=8YFLogxK
U2 - 10.1002/anie.200602963
DO - 10.1002/anie.200602963
M3 - Article
C2 - 17295369
AN - SCOPUS:34250374882
SN - 1433-7851
VL - 46
SP - 2210
EP - 2214
JO - Angewandte Chemie - International Edition
JF - Angewandte Chemie - International Edition
IS - 13
ER -