TY - GEN
T1 - Three nonlinear parameters to assess autonomic nervous system function of type 2 diabetes mellitus patients with a postural change from supineness to standing
AU - Cheng, Lu
AU - Xia, Li
AU - Haiying, Quan
PY - 2012
Y1 - 2012
N2 - Type 2 diabetes mellitus (T2DM) is a prevalent disease, which causes a high mortality and morbidity particularly if cardiovascular autonomic neuropathy (CAN) is present. Since heart rate variability (HRV) is a nonlinear and non-stationary signal, some nonlinear information can be explored from it with chaos theory. In this paper, electrocardiographs (ECGs) of healthy controls and T2DM patients both in supine position and standing position were firstly recorded. Then three nonlinear parameters including approximate entropy (ApEn), complexity (Comp) and sample entropy (SampEn) were calculated from HRV extracted by ECG. Finally autonomic nervous system (ANS) function of T2DM patients was assessed with above three nonlinear parameters. Subjects consisted of 35 T2DM patients and 38 healthy controls. The results showed that three nonlinear parameters were reduced in T2DM patients and decreased much less in T2DM patients compared with healthy controls when there was a postural change. The results also indicated that Comp and SampEn were more efficient than ApEn for assessing function of ANS.
AB - Type 2 diabetes mellitus (T2DM) is a prevalent disease, which causes a high mortality and morbidity particularly if cardiovascular autonomic neuropathy (CAN) is present. Since heart rate variability (HRV) is a nonlinear and non-stationary signal, some nonlinear information can be explored from it with chaos theory. In this paper, electrocardiographs (ECGs) of healthy controls and T2DM patients both in supine position and standing position were firstly recorded. Then three nonlinear parameters including approximate entropy (ApEn), complexity (Comp) and sample entropy (SampEn) were calculated from HRV extracted by ECG. Finally autonomic nervous system (ANS) function of T2DM patients was assessed with above three nonlinear parameters. Subjects consisted of 35 T2DM patients and 38 healthy controls. The results showed that three nonlinear parameters were reduced in T2DM patients and decreased much less in T2DM patients compared with healthy controls when there was a postural change. The results also indicated that Comp and SampEn were more efficient than ApEn for assessing function of ANS.
KW - assessment
KW - autonomic nervous system function
KW - heart rate variability
KW - postural change
KW - type 2 diabetes mellitus
UR - http://www.scopus.com/inward/record.url?scp=84886426158&partnerID=8YFLogxK
U2 - 10.1109/BMEI.2012.6513115
DO - 10.1109/BMEI.2012.6513115
M3 - Conference contribution
AN - SCOPUS:84886426158
SN - 9781467311816
T3 - 2012 5th International Conference on Biomedical Engineering and Informatics, BMEI 2012
SP - 610
EP - 613
BT - 2012 5th International Conference on Biomedical Engineering and Informatics, BMEI 2012
T2 - 2012 5th International Conference on Biomedical Engineering and Informatics, BMEI 2012
Y2 - 16 October 2012 through 18 October 2012
ER -
