TY - JOUR
T1 - Thrombolysis in Acute Myocardial Infarction
T2 - Current Status
AU - Kiernan, Thomas J.
AU - Gersh, Bernard J.
PY - 2007/7
Y1 - 2007/7
N2 - ST-segment elevation myocardial infarction (STEMI) is still a major public health problem in the modern world. Therapeutic options have changed much over the last 20 years, with a shift in favor of mechanical reperfusion over pharmacologic reperfusion. Thrombolytic therapy still has much to offer in the management of STEMI, however, because many patients do not have timely access to a facility with the required expertise for establishing mechanical reperfusion. This review highlights the history of thrombolytic therapy, adjunctive therapies, the relationship with mechanical reperfusion, and potential roles for thrombolysis in the future.
AB - ST-segment elevation myocardial infarction (STEMI) is still a major public health problem in the modern world. Therapeutic options have changed much over the last 20 years, with a shift in favor of mechanical reperfusion over pharmacologic reperfusion. Thrombolytic therapy still has much to offer in the management of STEMI, however, because many patients do not have timely access to a facility with the required expertise for establishing mechanical reperfusion. This review highlights the history of thrombolytic therapy, adjunctive therapies, the relationship with mechanical reperfusion, and potential roles for thrombolysis in the future.
UR - http://www.scopus.com/inward/record.url?scp=34447309609&partnerID=8YFLogxK
U2 - 10.1016/j.mcna.2007.02.005
DO - 10.1016/j.mcna.2007.02.005
M3 - Review article
C2 - 17640539
AN - SCOPUS:34447309609
SN - 0025-7125
VL - 91
SP - 617
EP - 637
JO - Medical Clinics of North America
JF - Medical Clinics of North America
IS - 4
ER -
