Thrombolysis in Acute Myocardial Infarction: Current Status

Thomas J. Kiernan; Bernard J. Gersh

doi:10.1016/j.mcna.2007.02.005

Thrombolysis in Acute Myocardial Infarction: Current Status

Thomas J. Kiernan
, Bernard J. Gersh

Mayo Clinic Rochester, MN

Research output: Contribution to journal › Review article › peer-review

Abstract

ST-segment elevation myocardial infarction (STEMI) is still a major public health problem in the modern world. Therapeutic options have changed much over the last 20 years, with a shift in favor of mechanical reperfusion over pharmacologic reperfusion. Thrombolytic therapy still has much to offer in the management of STEMI, however, because many patients do not have timely access to a facility with the required expertise for establishing mechanical reperfusion. This review highlights the history of thrombolytic therapy, adjunctive therapies, the relationship with mechanical reperfusion, and potential roles for thrombolysis in the future.

Original language	English
Pages (from-to)	617-637
Number of pages	21
Journal	Medical Clinics of North America
Volume	91
Issue number	4
DOIs	https://doi.org/10.1016/j.mcna.2007.02.005
Publication status	Published - Jul 2007
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/j.mcna.2007.02.005

Cite this

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abstract = "ST-segment elevation myocardial infarction (STEMI) is still a major public health problem in the modern world. Therapeutic options have changed much over the last 20 years, with a shift in favor of mechanical reperfusion over pharmacologic reperfusion. Thrombolytic therapy still has much to offer in the management of STEMI, however, because many patients do not have timely access to a facility with the required expertise for establishing mechanical reperfusion. This review highlights the history of thrombolytic therapy, adjunctive therapies, the relationship with mechanical reperfusion, and potential roles for thrombolysis in the future.",

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AU - Gersh, Bernard J.

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N2 - ST-segment elevation myocardial infarction (STEMI) is still a major public health problem in the modern world. Therapeutic options have changed much over the last 20 years, with a shift in favor of mechanical reperfusion over pharmacologic reperfusion. Thrombolytic therapy still has much to offer in the management of STEMI, however, because many patients do not have timely access to a facility with the required expertise for establishing mechanical reperfusion. This review highlights the history of thrombolytic therapy, adjunctive therapies, the relationship with mechanical reperfusion, and potential roles for thrombolysis in the future.

AB - ST-segment elevation myocardial infarction (STEMI) is still a major public health problem in the modern world. Therapeutic options have changed much over the last 20 years, with a shift in favor of mechanical reperfusion over pharmacologic reperfusion. Thrombolytic therapy still has much to offer in the management of STEMI, however, because many patients do not have timely access to a facility with the required expertise for establishing mechanical reperfusion. This review highlights the history of thrombolytic therapy, adjunctive therapies, the relationship with mechanical reperfusion, and potential roles for thrombolysis in the future.

UR - https://www.scopus.com/pages/publications/34447309609

U2 - 10.1016/j.mcna.2007.02.005

DO - 10.1016/j.mcna.2007.02.005

M3 - Review article

C2 - 17640539

AN - SCOPUS:34447309609

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EP - 637

JO - Medical Clinics of North America

JF - Medical Clinics of North America

IS - 4

ER -

Thrombolysis in Acute Myocardial Infarction: Current Status

Abstract

UN SDGs

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