Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation

Adriana J. Michielsen; Jacintha N. O'Sullivan; Elizabeth J. Ryan

doi:10.4161/onci.19570

Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation

Adriana J. Michielsen, Jacintha N. O'Sullivan, Elizabeth J. Ryan

Research output: Contribution to journal › Article › peer-review

Abstract

Tumors inhibit dendritic cell maturation and function in order to evade host immunity. We showed that conditioned media from tumor explant tissue, taken from metastatic colorectal cancer patients, significantly inhibits maturation of dendritic cells.

Original language	English
Pages (from-to)	751-753
Number of pages	3
Journal	OncoImmunology
Volume	1
Issue number	5
DOIs	https://doi.org/10.4161/onci.19570
Publication status	Published - 2012
Externally published	Yes

Keywords

CCL2
CXCL1
CXCL5
Dendritic cells
Tumour microenvironment
VEGF

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.4161/onci.19570

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title = "Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation",

abstract = "Tumors inhibit dendritic cell maturation and function in order to evade host immunity. We showed that conditioned media from tumor explant tissue, taken from metastatic colorectal cancer patients, significantly inhibits maturation of dendritic cells.",

keywords = "CCL2, CXCL1, CXCL5, Dendritic cells, Tumour microenvironment, VEGF",

author = "Michielsen, {Adriana J.} and O'Sullivan, {Jacintha N.} and Ryan, {Elizabeth J.}",

year = "2012",

doi = "10.4161/onci.19570",

language = "English",

volume = "1",

pages = "751--753",

journal = "OncoImmunology",

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T1 - Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation

AU - Michielsen, Adriana J.

AU - O'Sullivan, Jacintha N.

AU - Ryan, Elizabeth J.

PY - 2012

Y1 - 2012

N2 - Tumors inhibit dendritic cell maturation and function in order to evade host immunity. We showed that conditioned media from tumor explant tissue, taken from metastatic colorectal cancer patients, significantly inhibits maturation of dendritic cells.

AB - Tumors inhibit dendritic cell maturation and function in order to evade host immunity. We showed that conditioned media from tumor explant tissue, taken from metastatic colorectal cancer patients, significantly inhibits maturation of dendritic cells.

KW - CCL2

KW - CXCL1

KW - CXCL5

KW - Dendritic cells

KW - Tumour microenvironment

KW - VEGF

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U2 - 10.4161/onci.19570

DO - 10.4161/onci.19570

M3 - Article

AN - SCOPUS:84879655649

SN - 2162-4011

VL - 1

SP - 751

EP - 753

JO - OncoImmunology

JF - OncoImmunology

IS - 5

ER -

Tumor conditioned media from colorectal cancer patients inhibits dendritic cell maturation

Abstract

Keywords

UN SDGs

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